Nitric Oxide Supplements

Nitric Oxide was voted molecule of the year in 1998!  Experience the scientifically proven benefits of Nitric Oxide with AFFIRM. Dr. Brandeis’s physiology professor at UCLA won the Nobel Prize for discovering the way Nitric Oxide increases blood flow.  

TREAT Erectile Dysfunction with AFFIRM

AFFIRM helps men achieve strong and rigid erections by increasing blood flow to their penis. When you get an erection, blood flows into your penis and is temporarily trapped there, creating pressure in the surrounding chambers that causes your penis to expand. When you have ED, the blood flow is inadequate.

The dose recommended during treatment with Shock Wave Therapy is 2 pills twice a day. 

Each tablet is 895 mg of potent ingredients. Don’t be fooled by supplements in capsules containing lower concentrations of Nitric Oxide booster.   After treatment the recommended dose is 2 pills per day with or without food.  

AFFIRM is made with natural ingredients with no additives or preservatives.

AFFIRM is a 895 mg tablet consisting of:

L-Citrulline: an amino acid that is absorbed and then converted in the kidney into L-Arginine which combines with Oxygen to produce Nitric Oxide, a chemical that improves blood vessel health and increases blood flow.  Supplements that are based on Arginine are removed by the intestines and the liver and do not work as well as those based on L-Citrulline.  

Beet Root: an antioxidant that is also a potent source of Nitric Oxide

Asian Ginseng: The use of ginseng for ED has been well studied

Muira Puama: A Brazilian herb known as potency wood


L-Citrulline is a substance called a non-essential amino acid. Your kidneys change L-Citrulline into another amino acid called L-Arginine and a chemical called Nitric Oxide. These compounds are important to your heart and blood vessel health, and Nitric Oxide improves circulation which is the secret to hard, firm, healthy erections.


You might be wondering why AFFIRM® has L-Citrulline rather than L-Arginine. As it turns out, L-Arginine is broken down by the intestines and liver  and does not make it into the bloodstream intact. Instead, L-Citrulline goes into the kidneys where it is rapidly converted into L-Arginine.


That’s why L-Citrulline is the better choice for men looking to produce strong, hard erections. Scientific studies have proven L-Citrulline supplementation increases blood levels of L-Arginine more effectively than supplementation of L-Arginine alone. L-Citrulline can actually reverse blood vessel lining dysfunctions by activating another very important compound for growing blood vessels called vascular endothelial growth factor (VEGF).


VEGF repairs and improves the function of the blood vessels throughout the body, including within the corpus cavernosum, the sponge-like regions of erectile tissue that contain most of the blood in the penis during penile erection.


It has been scientifically demonstrated that L-Citrulline improves erectile hardness in men with mild erectile dysfunction, and improved penile blood pressures and Nitric Oxide levels in rat experimental models. 


L-Citrulline is safe with no reported side effects. However, the supplement may affect the way certain drugs work in your body. Do not take this supplement if you are taking nitrates for heart disease. Be aware that L-Citrulline in combination with ED drugs such as Cialis, Levitra, or Viagra, may lower your blood pressure and you should consult your doctor before combining the two.

Beet Root

Eating beet root extract has three main benefits:

As a source of nitrate, ingesting beet root provides a natural means of increasing nitric oxide (NO) availability in the bloodstream, which improves blood pressure and improves the function of the endothelium (or lining) of blood vessels. Increased blood flow into the penis increases erectile firmness.

Beetroot is an exceptionally rich source of antioxidant compounds which protect cellular components from oxidative injury. They suppress oxygen free radical formation and directly scavenge reactive oxygen and nitrogen species. This protects against oxidative damage to DNA, lipid and protein structures. The antioxidant capacity of beetroot juice is higher than almost all fruit and vegetable juices. 

Beet root, a natural NO donor, has been explored as a nutritional approach to preserve or restore endothelial function. Because NO mediates many of the endothelium’s functions, a depletion of NO availability that occurs with aging has been singled out as the principal cause of endothelial dysfunction. Replacing NO slows and in some cases reverses the aging process of blood vessels.

Asian Ginseng

Asian Ginseng has been investigated as a treatment for erectile dysfunction (ED). One pilot study using 60 patients with mild to moderate ED were given 3g of Korean Red Ginseng in three daily doses of 1g with meals for 12 weeks. Korean Red Ginseng appeared to be effective, with 66.6% of the patients in the KRG group reported improved erections while the placebo group was not significantly different from baseline. Another blinded study with a larger sample (86) noted that regular Panax Ginseng over a period of 8 weeks, dosed at 1,000mg twice daily (daily dose totaling 2g) found significant improvements in erectile function as assessed by the same rating scale.

A systematic review conducted on Korean Red Ginseng assessing seven randomized controlled trials found consistent benefits associated with Red Ginseng Extract, with doses ranging from 600mg taken three times a day (totaling 1,800mg) in four studies or 900mg taken three times daily (totaling 2,700mg) in two studies (one cited here).The conclusion was that there is a moderate level of evidence currently that Panax Ginseng has potential in helping erectile function (with implications on psychogenic erectile dysfunction as well as vascular) and appears to be more well researched than other herbs catered to promote erectile function; still needs some stronger research though.

Muira Puama

The herb Muira Puama (commonly known as Potency Wood) grows in regions surrounding Brazil and is said to enhance sexual function, especially in older men. It has usage as both a vitality and sexuality enhancer as well as a nerve tonic, treating chronic degenerative nervous ailments by the Amazonian people. Two studies on Muira Puama and sexuality in humans noted improvements, although conclusions drawn from these two are limited due to the inclusion of Ginkgo Biloba.  Studies show a small to moderate improvement in sexuality in both genders affecting approximately 2/3rds of participants. One study conducted in men using 1000-1500mg of a 4:1 extract of Muira Puama noted that 51% of respondents reported an improvement in erectile function after 2 weeks of usage.

Dr. Brandeis the founder and Chief Medical Officer of AFFIRM Science, makers of AFFIRM Nitric Oxide Boosting Supplement. Please see for details.

Please watch this 15-minute video on the health and sexual benefits of Nitric Oxide:

For details on the specific ingredients in AFFIRM, please review the following video:

Dr. Brandeis is the chief medical officer for AFFIRM Science and has formulated supplements specifically for men.  

AFFIRM is a natural nitric oxide booster that improves blood flow throughout the body including the brain and muscles.  It is ideal for men undergoing GAINSWave Shockwave Therapy to take four tablets of AFFIRM while they are undergoing treatment.

PreLONG is the first supplement specifically created for the treatment of premature ejaculation.  Premature ejaculation is a problem that affects 1 out of every 4 men between the ages of 20 and 50.  PreLONG contains an extract of St. John’s wort that improves brain serotonin levels that help improve ejaculatory control.  It also contains L citrulline which is a potent nitric oxide booster.

SupporT is a unique testosterone boosting supplement that contains Tongkat Ali and Ashwaganda which have been shown to improve testosterone level, as well as DHEA.  Since DHEA has the potential to increase estrogen levels, Dr. Brandeis included DIM which blocks the conversion of testosterone to estrogen.

SPUNK supports prostate health with Beta Sitosterol and Pygeum and Flax.  These are all products scientifically shown to improve prostate function. It does not include saw palmetto which has been shown in meta-analyses to have no efficacy.