Information about Clomid
Clomid is an alternative to testosterone replacement therapy that preserves fertility. TRT reduces sperm production and impacts fertility. The pituitary gland in the brain directs testicular function by producing LH to stimulate testosterone production from the testicle and FSH to stimulate sperm production. If the pituitary sees a high testosterone level, it stops telling the testes to produce testosterone. This also affects sperm production. This explains why testes shrink a bit on TRT.
IF YOU WANT TO BOOST TESTOSTERONE LEVELS BUT DO NOT WANT TO COMPROMISE FERTILITY, WHAT CAN YOU DO?
Clomid (clomiphene citrate) uses a different approach to increase testosterone and spermatogenesis. It was originally developed and tested to increase ovulation and, thereby, improve fertility in women. The result in men is a modest improvement in testosterone levels while preserving sperm production. We can usually achieve a 100% increase in T levels with Clomid. In some cases, one may see up to a 200% increase. This increase is not as high as pellets or injections but it can make a big difference depending on how low you are. So if you had an initial level of 300, we would hope to see an increase to 600, +/-. Some clients may even see a larger increase.
WHAT ARE THE BENEFITS OF CLOMID OVER TRADITIONAL TESTOSTERONE INJECTIONS OR PELLET TRT?
Clomid for men stimulates the body’s own production of testosterone. Clomid is a pill taken daily. It is generic and cheap. No shots. It does not interfere with the body’s checks and balances of testosterone. Fertility is preserved. No testicular shrinkage. It has few, if any, side effects and this is usually dose-related. Clomid, by increasing T levels, can produce the same/similar effects as traditional TRT. Each patient is different and the response will vary depending on current testosterone level. It is inexpensive and usually covered by health insurance.
IS THERE ANY DOWNSIDE TO CLOMID THERAPY?
In lower levels of testosterone, it takes longer to see the benefits of Clomid than with injection therapy. It may also not work, especially in patients over 60 and those with compound medical issues. Some patients may not see a boost in libido as Clomid does have some mild estrogenic properties. Of course, we follow the labs, just like in TRT, and would correct for an elevated estradiol level if needed (anastrozole). There have been rare reports of vision changes. If this happens, the patient should note very specifically what occurred, how long it lasted, etc. and then stop the Clomid until you speak with your doctor.
WHO SHOULD USE CLOMID?
A typical candidate for Clomid is younger and planning on having children soon or in the future. Patients who just do not want to deal with injection or pellet therapy and are willing to accept a lower T level. Patients who have been on TRT and have decided to have children but want to maintain some increase in testosterone levels. Men who have known low sperm counts. Patients who have a varicocele (a problem with the blood vessel around the testes) that can cause infertility.
CLOMID FOR MEN DOSAGE
The dosage range is 12.5mg – 50mg per day. I prefer to start at 25mg every other day for a short trial period and then increase to daily dosing. Dosage can be adjusted based on any side effects, lab results, and an overall improvement in the “T-effect”. You will read any number of protocols that involve more complicated patterns of dosing. I prefer to keep it simple.
Some doctors recommend taking Vitamin E to improve the success of Clomid. More than 400 iu is not recommended, a much smaller dose is fine.